Katie Dell, from Flint, North Wales, suffers with the condition aquagenic urticaria, which is so rare it affects just 35 people in the whole world.
She cannot even cry because her own tears bring her out into a painful rash. Long soaks in the bath are out of the question because they trigger burning inflammation.
The 27-year-old was even forced to give up her job as a dance teacher because her perspiration caused a painful reaction on her skin.
The condition is getting worse and she fears it will end up killing her.
She said: ‘Sometimes I feel like a prisoner in my own home. I have days where I want to crawl into bed and cry but of course, I can’t.
‘Someone said I could die from it but I don’t want to know about my life expectancy. Until they find a cure I just have to live with it. I’m taking each day as it comes.’
Mrs Dell’s symptoms began at 16 when she had her tonsils removed. Doctors suspect the penicillin she was given may have disrupted histamine levels in her body.
Her husband, Andy, 32, has given up his job as a delivery driver to be her full-time carer.
She said: ‘People didn’t understand my condition and would give me a funny look when I told them I couldn’t shower.
‘My condition is worsening but I don’t want to think about what I’ll be like in 10 or 15 years.
‘Andy has been amazing and does all the things I’m not allowed to do, like the washing up.
‘I have to be in and out of the bath in two minutes and Andy has to wash my hair for me.’