After all the votes were counted, he had polled 50.03% of the vote, 4,109 votes over the threshold required for outright victory.
But the official result will not come until 11:00 on Saturday (08:00 GMT).
Rival candidate Raila Odinga is likely to file a legal challenge if he loses.
As at 02:41am (Kenyan time) Official Presidential Results reveal: Uhuru 6,173,433; Raila 5,340,546 291 constituencies.
Kenyatta won the Kenyan general election, 2013 with 50.03% of the vote avoiding a run-off against Raila Odinga.
He is the Member of Parliament for Gatundu South Constituency and former Chairman of Kenya African National Union (KANU), which was a part of the Party of National Unity (PNU).
Kenyatta is the son of Jomo Kenyatta, Kenya’s first president (1964–1978). His name, Uhuru, is Swahili for “freedom”.